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Aneurysm & Stroke Clinical Trials

Norton Neuroscience Institute offers neuroscience clinical research trials for qualified patients. Patients can participate in studies that cover a wide range of neurological and neurosurgical conditions such as aneurysm, stroke and multiple sclerosis. For more information about our research and clinical trials, call (502) 446-8991 or email NNIResearch@nortonhealthcare.org.


Aneurysm

Title: New Generation Hydrogel Endovascular Aneurysm Treatment Trial

Sponsor: Northwestern University

Physician Investigator: Shervin Dashti, M.D., Ph.D., Tom Yao, M.D.

Research Detail: The purpose of this research study is to compare the effectiveness of the HydroCoil Embolization System to the standard bare platinum coil in order to see which method is better at preventing future rupturing or leaking of aneurysms.


Title: Reverse Medical Barrell Vascular Reconstruction Device for Adjunctive Treatment to Embolic Coils for Wide Neck, Intracranial, Bifurcating/Branching Aneurysms of MiddleCerebral and Basilar Arteries

Sponsor: Reverse Medical

Physician InvestigatorShervin Dashti, M.D., Ph.D.Tom Yao, M.D.

Research Detail: The purpose of the study is to evaluate the safety (short and long term side effects) and effectiveness  (how well it  helps the coils stop the blood flow inside the aneurysm) of implanting the BARREL Vascular Reconstruction Device (VRD), an investigational device, in addition to the coiling treatment for your wide neck bifurcating aneurysm. 



Title
: Low Profile Visualized Intraluminal Support Device

Sponsor: MicroVention, Inc

Physician InvestigatorShervin Dashti, M.D., Ph.D.Tom Yao, M.D.

Research Detail: Humanitarian Use Device to treat brain aneurysm



Title
: Cordis Enterprise Vascular Reconstruction Device and Delivery System

Sponsor: Cordis

Physician Investigator: Tom Yao, M.D., Shervin Dashti, M.D., Ph.D.

Research Details: This is a Humanitarian Use Device used to treat brain aneurysms.


 

Title: The Neuroform Microdelivery Stent System, a Humanitarian Use Device

Sponsor: Boston Scientific

Physician InvestigatorShervin Dashti, M.D., Ph.D.Tom Yao, M.D.

Research Details: This is a Humanitarian Use Device used to treat brain aneurysms 


Title: The Wingspan Stent System and Gateway PTA Balloon Catheter, a Humanitarian Use Device

Sponsor: Boston Scientific

Physician InvestigatorShervin Dashti, M.D., Ph.D.Tom Yao, M.D.

Research Details: This is a Humanitarian Use Device used to treat brain aneurysms.


Stroke

Title: Systematic Evaluation of Patients Treated with Neurothrombectomy Devices for Acute Ischemic Stroke Registry

Sponsor: Covidien

Physician Investigator:  Tom Yao, M.D.

Research Details: The purpose of this registry is to track outcomes of patients who have neurothrombectomy for ischemic stroke. 


Stroke/TIA

Title: A randomized, double blind, multinational study to prevent major vascular events with ticagrelor compared to aspirin in patients with acute ischemic stroke or TIA

Sponsor: Astra Zeneca

Physician InvestigatorNadeem A. Talpur, M.D.

Research Details: The purpose of this study is to evaluate patient outcomes when taking ticragelor or aspirin following stroke or TIA.

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