Pantothenic acid and biotin are types of B vitamins. They are water-soluble, which means that the body can't store them. If the body can't use all of the vitamin, the extra leaves the body through the urine. These vitamins must be replaced in the body every day.
Pantothenic acid; Pantethine; Vitamin B5
Pantothenic acid and biotin are essential for growth. They help the body break down and use food. This is called metabolism.
Pantothenic acid also plays a role in the production of hormones and cholesterol.
Biotin is found in foods that are good sources of B vitamins, including:
Organ meats (liver, kidney)
Pantothenic acid is found in foods that are good sources of B vitamins, including the following:
Broccoli, kale, and other vegetables in the cabbage family
Legumes and lentils
White and sweet potatoes
There are no known deficiencies of either pantothenic acid or biotin.
Large doses of pantothenic acid do not cause symptoms, other than (possibly) diarrhea. There are no known toxic symptoms from biotin.
Recommendations for pantothenic acid and biotin, as well as other nutrients, are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board at the Institute of Medicine. DRI is a term for a set of reference intakes that are used to plan and assess the nutrient intakes of healthy people. These values, which vary by age and gender, include:
Recommended Dietary Allowance (RDA): average daily level of intake that is enough to meet the nutrient needs of nearly all (97 - 98%) healthy people.
Adequate Intake (AI): established when there is not enough evidence to develop an RDA. It is set at a level that is thought to ensure enough nutrition.
Dietary Reference INtakes for pantothenic acid:
Age 0-6 months: 1.7* milligrams per day (mg/day)
Age 7-12 months 1.8* mg/day
Age 1-3 years: 2* mg/day
Age 4-8 years: 3* mg/day
Age 9-13 years: 4* mg/day
Age 14 and older: 5* mg/day
*Adequate Intake (AI)
Age 0-6 months: 5* micrograms per day (mcg/day)
Age 7-12 months: 6* mcg/day
Age 1-3 years: 8* mcg/day
Age 4-8 years: 12* mcg/day
Age 9-13 years: 20* mcg/day
Age 14 -18 years: 25* mcg/day
19 and older: 30* mcg/day
*Adequate Intake (AI)
The best way to get the daily requirement of essential vitamins is to eat a balanced diet that contains a variety of foods.
Specific recommendations depend on age, gender, and other factors (such as pregnancy). Women who are pregnant or breast-feeding need higher amounts. Ask your health care provider which amount is best for you.
Escott-Stump S, ed. Nutrition and Diagnosis-Related Care. 6th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2008.
Sarubin Fragaakis A, Thomson C. The Health Professional's Guide to Popular Dietary Supplements. 3rd ed. Chicago, Il: American Dietetic Association;2007.
Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes: Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, DC, 2000.
Alison Evert, MS, RD, CDE, Nutritionist, University of Washington Medical Center Diabetes Care Center, Seattle, Washington. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.