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Secretin stimulation test

Secretin stimulation test is a test that measures the ability of the pancreas to respond to secretin. Secretin is a hormone secreted by the small intestines in the presence of partially digested food from the stomach; this hormone normally stimulates the pancreas to secrete a fluid with a high concentration of bicarbonate. This fluid neutralizes the acidity from the stomach that is necessary for a number of enzymes to function in the breakdown and absorption of food. In order to perform the test a tube is passed through the nose into the stomach then into the duodenum. Secretin is administered and the contents of the duodenal secretions are aspirated and analyzed over a period of about 2 hours. People with diseases involving the pancreas (for example chronic pancreatitis, cystic fibrosis, pancreatic cancer) may have abnormal pancreatic function.


Review Date: 10/8/2012
Reviewed By: George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, and Stephanie Slon.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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